Raymond Chung, PHD

Education

PHD, Yale University
BS, University of Notre Dame

About

Teaching Interests: General Chemistry; Organic Chemistry lab.

Research

I am interested in hypervalent iodine chemistry and its application to the synthesis of interesting organic molecules. While hypervalent iodine chemistry has been used extensively in organic synthesis, the electronic structure of some hypervalent iodine reagents and the mechanisms by which they react are sometimes unclear. My research endeavors center around investigating the electronic structure and reactivity of certain hypervalent iodine reagents and understanding how they work.

Another interest of mine is the synthesis of organic molecules that have the ability to inhibit the formation of prion fibrils, the accumulation of which has been implicated in a class of diseases known as transmissible spongiform encephalopathies, or TSEs. TSEs are a group of fatal neurodegenerative diseases in mammals, diseases which include Creutzfeldt-Jacob disease, Kuru, Gersmann-Sträussler-Scheinker (GSS) syndrome and fatal familial insomnia.

Professional Experience

The Cooper Union for the Advancement of Science and Art, New York, NY.
Adjunct Professor of Chemistry (Jan 2011 – Dec. 2011, Jan 2013 - Present)

Manhattanville College, Purchase, NY.
Adjunct Lecturer (Aug 2010 – Dec. 2011)

SUNY - Purchase College, Purchase, NY.
Adjunct Lecturer (Jan 2011 – May 2011)

Cooper & Dunham LLP, New York, NY
Scientific Advisor (July 2008 – June 2010)

United States Patent and Trademark Office, Alexandria, VA.
Patent Examiner (Sept. 2007 – July 2008)

Yale School of Medicine, Department of Pharmacology, New Haven, CT.
Postdoctoral Research Associate (Oct. 2004 – Jul. 2006)

Yale University, New Haven, CT.
Teaching Fellow (Aug. 1999 – Oct. 2004)

Publications & Professional Activities

1. “Alternative Synthetic Routes to 2',3’-Didehydro-2',3'-dideoxy-5-hydroxymethyluridine.” Chung, R.; Anderson, K. S. Tetrahedron Lett. 2006; 47 (47); 8361-8363.

2. “Modulation of Human Immunodeficiency Virus Type 1 Synergistic Inhibition by Reverse Transcriptase Mutations” Basavapathruni, A.; Vingerhoets, J.; de Bethune, M.-P.; Chung, R.; Bailey, C. M.; Kim, J.; Anderson, K. S. Biochemistry 2006; 45(23); 7334-7340.

3. “Synthesis and Antiviral Activity of Helioxanthin Analogues.” Yeo, H.; Li, Y.; Fu, L.; Zhu, J.-L.; Gullen, E. A.; Dutschman, G. E.; Lee, Y.; Chung, R.; Huang, E.-S.; Austin, D. J.; Cheng, Y.-C.; J. Med. Chem. 2005; 48 (2); 534-546.

4. “Hypervalent Iodine-mediated Vicinal Syn Diazidation: Application to the Total Synthesis of (±)-Dibromophakellstatin.” Chung, R.; Yu, E.; Incarvito, C. D.; Austin, D. J.; Org. Lett. 2004, 6 (22); 3881-3884.

Professional Memberships

Member, American Chemical Society

Registered Patent Agent, United States Patent and Trademark Office